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1955-1960 Pioneering research on vitamin B12 synthesis
1960 Promoted to associate professor; became full professor in 1965
1972 Completed total synthesis of vitamin B¿¿
1980s-1990s Research on the chemical origins of nucleic acids; developed artificial genetic polymers such as TNA
1986 Awarded the Wolf Prize in Chemistry for work on natural product synthesis and reaction mechanisms
1992 Retired from ETH Zurich; continued research as professor at Scripps Research Institute 1996-2009
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